{"id":2500,"date":"2018-10-30T14:50:30","date_gmt":"2018-10-30T14:50:30","guid":{"rendered":"http:\/\/madhousereport.com\/?p=2500"},"modified":"2018-10-30T14:50:30","modified_gmt":"2018-10-30T14:50:30","slug":"nec-transgene-announce-collaboration-field-individualized-cancer-immunotherapy-leveraging-necs-ai-transgenes-myvac-platform","status":"publish","type":"post","link":"https:\/\/theblogonline.com\/?p=2500","title":{"rendered":"NEC, Transgene Announce Collaboration In Field Of Individualized Cancer Immunotherapy, Leveraging NEC’s AI And Transgene\u2019s myvac\u2122 Platform"},"content":{"rendered":"

TOKYO, Japan & STRASBOURG, France–(BUSINESS WIRE<\/span><\/a><\/span>\/AETOSWire<\/span><\/a><\/span>)– NEC Corporation<\/span><\/a> (NEC)(TOKYO:6701) and Transgene (Euronext Paris:TNG) today announced the signing of a Memorandum of Understanding (MOU) for a strategic collaboration aimed at the treatment of solid cancers. The companies will cooperate in clinically assessing the predictive capabilities of NEC\u2019s artificial intelligence (AI) and the therapeutic potential of Transgene\u2019s myvac<\/i>\u2122 MVA-based viral vector platform in an individualized immunotherapy for the treatment of solid cancers. The experimental products from this collaboration are expected to enter clinical trials in 2019. <\/span><\/p>\n

NEC and Transgene will co-invest in the first stage of development of an individualized immunotherapy, which includes clinical trials focusing on ovarian cancer and HPV-negative head and neck cancer. <\/span><\/p>\n

Immunotherapy is rapidly becoming the treatment of choice to fight cancer as it activates the patient\u2019s own immune system to attack cancer cells. <\/span><\/p>\n

NEC and Transgene have capitalized on the recent progress in AI and advances in genome sequencing to create individualized immunotherapy, which is adapted to the unique characteristics of each patient\u2019s mutational landscape as well as their predicted immune responses. The product is based on a viral vector (MVA) developed by Transgene with a proven clinical safety track record and is known for its efficient immunogenicity and anti-tumor efficacy in patients. <\/span><\/p>\n

The viral vector will be used to target neoantigens identified using NEC\u2019s proprietary algorithm. NEC has been developing solutions in the drug discovery field for close to two decades. NEC\u2019s neoantigen prediction system was developed and validated based on publicly available databases, as well as internal wet lab datasets, some of which were already used to identify clinically relevant antigens in other oncology indications. <\/span><\/p>\n

These planned clinical trials leverage the world-leading expertise and technologies of a network of companies and research centers, including: <\/span><\/p>\n

NEC\u2019s cutting-edge AI technology, \u201cNEC the WISE\u201d, for identifying and prioritizing patient-specific neoantigens, and <\/span><\/p>\n

Transgene\u2019s unrivaled MVA-based, viral vector technology and the myvac<\/i>\u2122 platform. <\/span><\/p>\n

\u201cThe emerging personalized medicine field holds great potential for the application of NEC\u2019s core technology, and we are pleased to be working with Transgene with the goal of developing state-of-the-art personalized immunotherapies,\u201d said Motoo Nishihara, Senior Vice President, Head of NEC Laboratories. <\/span><\/p>\n

\u201cEngaging the body\u2019s own immune system in the fight against cancer has shown great promise and sparked unprecedented interest among oncology drug makers. This makes it imperative for NEC to become part of the immunotherapy race as soon as possible,\u201d said Osamu Fujikawa, Senior Vice President, Business Innovation Unit, NEC Corporation. <\/span><\/p>\n

\u201cThis collaboration brings together artificial intelligence and our expertise in viral vector engineering to enable the development of a truly innovative treatment based on the myvac\u2122<\/i> platform. We believe that our collaboration with NEC will allow us to provide an efficacious and robust therapy for the many patients who have solid tumors and could benefit from this cutting-edge individualized approach, and to successfully advance the development of the myvac\u2122 <\/i>platform <\/i>to the market\u201d said \u00c9ric Qu\u00e9m\u00e9neur, Pharm.D., Ph.D., Executive VP, Chief Scientific Officer of Transgene. <\/span><\/p>\n

View source version on businesswire.com: https:\/\/www.businesswire.com\/news\/home\/20181029005305\/en\/<\/span><\/a><\/span><\/p>\n

*Source: AETOSWire<\/span><\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

TOKYO, Japan & STRASBOURG, France–(BUSINESS WIRE\/AETOSWire)– NEC Corporation (NEC)(TOKYO:6701) and Transgene (Euronext Paris:TNG) today announced the signing of a Memorandum of Understanding (MOU) for a strategic collaboration aimed at the treatment of solid cancers. The companies will cooperate in clinically assessing the predictive capabilities of NEC\u2019s artificial intelligence (AI) and the therapeutic potential of Transgene\u2019s […]<\/p>\n","protected":false},"author":1,"featured_media":2501,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[1855,1178,1856,1854,1857],"class_list":["post-2500","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-metro","tag-cancer-immunotherapy","tag-nec","tag-necs-ai","tag-transgene","tag-transgenes-myvac-platform"],"_links":{"self":[{"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/posts\/2500"}],"collection":[{"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/theblogonline.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2500"}],"version-history":[{"count":1,"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/posts\/2500\/revisions"}],"predecessor-version":[{"id":2502,"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/posts\/2500\/revisions\/2502"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/theblogonline.com\/index.php?rest_route=\/wp\/v2\/media\/2501"}],"wp:attachment":[{"href":"https:\/\/theblogonline.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theblogonline.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theblogonline.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}